Puwainaphycin F

Article number:

5600040

CAS No.:

1379577-47-5

Formula:

C53H87N13O15

Chemical description:

2-[(3S,6S,9S,16S,19Z,22S,25Z,28S,31S)-3,22-bis(2-amino-2-oxoethyl)-13-dodecan-2-yl-19,25-di(ethylidene)-12-hydroxy-6-[(1R)-1-hydroxyethyl]-4,9-dimethyl-28-(2-methylpropyl)-2,5,8,11,15,18,21,24,27,30-decaoxo-1,4,7,10,14,17,20,23,26,29-decazabicyclo[29

Molecular weight:

1146,34 g/mol

Puwainaphycin F is a cyclic lipopeptide. Puwainaphycin F is causing necrotic cell death to mammalina cells. Lab trials has shown necrotic cell death after about 10 h. The IC50=2.2 µM. Potential mode of action/Key words: Necrosis inducer

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Puwainaphycin F

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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