Pyrrolobenzodiazepine Dimer

Article number:

5600009

Formula:

C31H32N4O6

Chemical description:

(6aS)-3-[3-[[(6aS)-2-methoxy-8-(4-methoxyphenyl)-11-oxo-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]propoxy]-8-(4-aminophenyl)-2-methoxy-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-11-one

Molecular weight:

556,61 g/mol

Pyrrolobenzodiazepine (PBDs) are a class of DNA-crosslinking agents that are significantly more potent than systemic chemotherapeutic drugs. Novel results demonstrate that PBDs can be effectively used for antibody-targeted therapy. Potential mode of action/Key words: Targeting DNA, DNA crosslinking, Anticancer

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Pyrrolobenzodiazepine Dimer

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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