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Pyrrolobenzodiazepine (PBDs) are a class of DNA-crosslinking agents that are significantly more potent than systemic chemotherapeutic drugs. Novel results demonstrate that PBDs can be effectively used for antibody-targeted therapy. Potential mode of action/Key words: Targeting DNA, DNA crosslinking, Anticancer
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...