Home » ADCs » Pyrrolobenzodiazepine Dimer, with NH2 function

Pyrrolobenzodiazepine Dimer, with NH2 function

Article number:

5600084

Formula:

C₄₂H₃₉N₅O₇

Molecular weight:

725,79 g/mol

Pyrrolobenzodiazepine are a class of DNA-crosslinking agents that are significantly more potent than systemic chemotherapeutic drugs. Novel results demonstrate that PBDs can be effectively used for antibody-targeted therapy. Our novel compound has a NH2 function as coupling group for ADCs. Potential mode of action/Key words: Targeting DNA, DNA crosslinking

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Pyrrolobenzodiazepine Dimer, with NH2 function

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...