O Cl OH HO O O O

Radicicol

Article number:

5500739

CAS No.:

12772-57-5

Formula:

C18H17ClO6

Chemical description:

IUPAC: (1aR,2E4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione

Synonyms:

Monorden; Radisicol; Monorden; Monoroden

Molecular weight:

364,79 g/mol

Radicicol is also known as monorden. Radicicol is a natural product that binds to Hsp90 and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis. Radicicol is a macrolactone antibiotic. Bioactivity: antibiotic, antifungal, cytotoxic, nemcytotoxicicidal, malaria. Compound class: Macrolide

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Radicicol

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