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Radicicol
Article number:
5500739
CAS No.:
12772-57-5
Formula:
C18H17ClO6
Chemical description:
IUPAC: (1aR,2E4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione
Synonyms:
Monorden; Radisicol; Monorden; Monoroden, RHI-12648; FO-4910
Molecular weight:
364,79 g/mol
Radicicol is also known as monorden. Radicicol is a natural product that binds to Hsp90 and alters its function. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis. Radicicol is a macrolactone antibiotic. Bioactivity: antibiotic, antifungal, cytotoxic, nemcytotoxicicidal, malaria. Compound class: Macrolide
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