Rapamycin-fluorescein

Article number:

5500527

Formula:

C80H103N3O21

Synonyms:

C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin.

Molecular weight:

1442,68 g/mol

Rapamycin-fluorescein is a flurorescein labeled rapamycin. It is an excellent fluorescent probe to characterise FK506-binding proteins. It has moderate affinity for the FK1 domains of FKBPS1 (177 nM) and FKBP2 (469 nM) and it is suitablefor high-throughput screening. Ref.: Kozany, et al, ChemieBioChem, 2009 10, 1402.

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Rapamycin-fluorescein

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