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Rubitecan is a topoisomerase I inhibitor. Rubitecan induces protein-linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer. Potential mode of action/Key words_ Targeting DNA, Topoisomerase inhibitor, Antitumoral
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...