N N O O O HO O 2 N

Rubitecan

Article number:

5600161

CAS No.:

91421-42-0

Formula:

C20H15N3O6

Synonyms:

9-nitrocamptothecin

Molecular weight:

393.36 g/mol

Rubitecan is a topoisomerase I inhibitor. Rubitecan induces protein-linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer. Potential mode of action/Key words_ Targeting DNA, Topoisomerase inhibitor, Antitumoral

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Rubitecan

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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