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Salinomycin induces cell death in some types of cancer cells such as breast, lung, gastric cancer, leukemia and osteosarcoma. Salinomycin inhibits multidrug resistance protein 1 and induces apoptosis by the generation of reactive oxygen species that cause DNA damage and inactivation of Stat3. Salinomycin produced by Streptomyces albus is a carboxylic polyether ionophore with antibiotic and anti-cancer properties.
Mycotoxins are secondary metabolites of molds fungis which have a very toxic effect on human being. The species of Mycotoxins subdivide to aflatoxins, fumonisines, ochratoxins and fusarium toxins. The name ...