SG-3249 (Teserine)

Article number:

56000205

CAS No.:

1595275-62-9

Formula:

C75H101N9O23

Synonyms:

Teserine

Molecular weight:

1496,75 g/mol. g/mol

Tesirine (SG3249) is an Antibody-Drug Conjugate containing pyrrolobenzodiazepine dimer as payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines.

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SG-3249 (Teserine)

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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Reagents for ADCs

Cfm Oskar Tropitzsch offers ecxept payloads also other important reagents for the Conjugation of ADCs. One example is Dithiothreitol (DTT, Clealand`s reagent). DTT is a redox reagent in molecular biology. DTT ...

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