N NH O NH OH O O

Taltobulin

Article number:

5600198

CAS No.:

228266-40-8

Formula:

C27H43N3O4

Synonyms:

HTI-286; SPA-110

Molecular weight:

473.66 g/mol

Taltobulin is a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.

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Taltobulin

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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Reagents for ADCs

Cfm Oskar Tropitzsch offers ecxept payloads also other important reagents for the Conjugation of ADCs. One example is Dithiothreitol (DTT, Clealand`s reagent). DTT is a redox reagent in molecular biology. DTT ...

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