Thiocolchicine

Article number:

5600036

CAS No.:

2730-71-4

Formula:

C22H25NO5S

Chemical description:

N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

Synonyms:

10-Demethoxy-10-(methylthio)colchicine, 10-Thio-colchicine, N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-acetamide, NSC 186301

Molecular weight:

415,50 g/mol

Thiocolchicine is an antimitotic alkaloide. Thiocolchicine is an inhibitor of microtubules by specific binding to tubulin. Thiocolchicine is a topoisomerase I inhibitor. Potential mode of action/Key words: Targeting Tubulin, Topoisomerase I inhibitor, Induces Apoptosis, Cytotoxic

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Thiocolchicine

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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