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Tofactinib, free base
Tofacitinib is a novel JAK3 inhibitor. Precilincal and clinical data strongly support that Tofacitinib, as an immunosuppressant, prevents organ trasplant rejection and alleviates the symptoms of autoimmune diseses, such as rheumatoid arthritis and posriasis.
Protein Kinase Inhibitors
Protein kinases are enzymes that transfer phosphate groups from high-energy donors (typically nucleoside triphosphates) to surface exposed Serine, Threonine or Tyrosine side chains of other proteins and thus alter their ...