Tripolin A

Article number:

5600037

CAS No.:

1148118-92-6

Formula:

C15H11NO3

Chemical description:

[(3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one]

Molecular weight:

253,25 g/mol

Triptolin A is described as an specific non-ATP competitve Aurora A kinase inhibitor. Tripolin A doesn`t significantly inhibit Aurora B kinase in mammalian cells. Tripolin A reduces localization of pAurora A on spindle microtubules, affects centrosome integrity, spindle formation and lenght and MT dynamitcs in interphase. Tripolin A is a novel small molecule inhibitor of aurora A kinase.

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Tripolin A

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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