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Article number:
5600046
CAS No.:
1310693-92-5
Formula:
C20H21N3O2*HCl
Chemical description:
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;hydrochloride
Synonyms:
TSA HCl; Tubastatin A hydrochloride
Molecular weight:
371,86 g/mol
Tubastatin A hydrochloride is a potent and selective inhibitor of HDAC6. IC50=15 nM. Tubastatin A HCl induced the acetylation of alpha-tubulin and protected primary cortical neurons against glutathione depletion-induced oxidative stress. Potential mode of action/Key words: Targeting DNA, Histon modification, Targeting Tubulin
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...