Tubastatin A HCl

Article number:

5600046

CAS No.:

1310693-92-5

Formula:

C20H21N3O2*HCl

Chemical description:

N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide;hydrochloride

Synonyms:

TSA HCl; Tubastatin A hydrochloride

Molecular weight:

371,86 g/mol

Tubastatin A hydrochloride is a potent and selective inhibitor of HDAC6. IC50=15 nM. Tubastatin A HCl induced the acetylation of alpha-tubulin and protected primary cortical neurons against glutathione depletion-induced oxidative stress. Potential mode of action/Key words: Targeting DNA, Histon modification, Targeting Tubulin

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Tubastatin A HCl

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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