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Vatalanib, dihydrochloride salt
PTK 787; ZK222584
Vatalanib is a potent, selective, orally active inhibitor of VEGFR tyrosine kinases VEGFR-1 and VEGFR-2 with slightly higher potency against the latter.
Protein Kinase Inhibitors
Protein kinases are enzymes that transfer phosphate groups from high-energy donors (typically nucleoside triphosphates) to surface exposed Serine, Threonine or Tyrosine side chains of other proteins and thus alter their ...