Verticillin A

Article number:


CAS No.:




Chemical description:


Molecular weight:

696,84 g/mol

Verticillin A is a fungal epipolythiodioxopiperazine (ETP) metabolite with antibiotic properties. Verticillin A is inactive against fungi, Verticillin A showed considerable anti-tumor properties against HeLa Cells. Verticillin A is a selective HMTase inhibitor. Verticillin A selectively inhibits SUV39H1, SUV39H2, G9a, and GLP in vitro. Verticillin A is structurally very similar to Chaetocin, differing only in the position of two hydroxyl groups.The potential mode of action is connected to the chromatin remodeling. Potential mode of action/Key words: Targeting DNA, HMTase inhibitor, Antibiotic, Antitumoral

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Verticillin A


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