Xanthohumol

Article number:

7500907

CAS No.:

6754-58-1

Formula:

C21H22O5

Synonyms:

(E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one;

Molecular weight:

354,40 g/mol

Insect antifeedant potential of xanthohumol and isoxanthohumol and their derivatives. Stompor M, Dancewicz K, Gabrys B, Aniol M. J Agric Food Chem. 2015 Jul 15. [Epub ahead of print] *** Xanthohumol improves diet-induced obesity and fatty liver by suppressing sterol regulatory element-binding protein (SREBP) activation. Miyata S, Inoue J, Shimizu M, Sato R. J Biol Chem. 2015 Jul 3. pii: jbc.M115.656975. [Epub ahead of print] *** An Improved Nonradioactive Screening Method Identifies Genistein and Xanthohumol as Potent Inhibitors of Iodothyronine Deiodinases. Renko K, Schäche S, Hoefig CS, Welsink T, Schwiebert C, Braun D, Becker NP, Köhrle J, Schomburg L. Thyroid. 2015 Jun 25. [Epub ahead of print] *** Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells. Kunnimalaiyaan S, Trevino J, Tsai S, Gamblin TC, Kunnimalaiyaan M. Mol Cancer Ther. 2015 Jun;14(6):1395-403. doi: 10.1158/1535-7163.MCT-14-0915. Epub 2015 Apr 17. *** Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions. Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, Katagiri T. Sci Rep. 2014 Dec 8;4:7355. doi: 10.1038/srep07355. *** Xanthohumol improved cognitive flexibility in young mice. Zamzow DR, Elias V, Legette LL, Choi J, Stevens JF, Magnusson KR. Behav Brain Res. 2014 Dec 15;275:1-10. doi: 10.1016/j.bbr.2014.08.045. Epub 2014 Sep 1. *** Investigation of the anxiolytic effects of xanthohumol, a component of humulus lupulus (Hops), in the male Sprague-Dawley rat. Ceremuga TE, Johnson LA, Adams-Henderson JM, McCall S, Johnson D. AANA J. 2013 Jun;81(3):193-8.

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Xanthohumol

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