6-Gingerol

Article number:

7550446

CAS No.:

23513-14-6

Formula:

C17H26O4

Chemical description:

Molecular weight:

294,39 g/mol

γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells. Yusof KM, Makpol S, Jamal R, Harun R, Mokhtar N, Ngah WZ. Molecules. 2015 Jun 3;20(6):10280-97. doi: 10.3390/molecules200610280. *** [6]-gingerol dampens hepatic steatosis and inflammation in experimental nonalcoholic steatohepatitis. Tzeng TF, Liou SS, Chang CJ, Liu IM. Phytomedicine. 2015 Apr 15;22(4):452-61. doi: 10.1016/j.phymed.2015.01.015. Epub 2015 Feb 26. *** 6-Gingerol reduces Pseudomonas aeruginosa biofilm formation and virulence via quorum sensing inhibition. Kim HS, Lee SH, Byun Y, Park HD. Sci Rep. 2015 Mar 2;5:8656. doi: 10.1038/srep08656. *** 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation. Fan J, Yang X, Bi Z. Tumour Biol. 2015 Feb;36(2):1135-41. doi: 10.1007/s13277-014-2723-1. Epub 2014 Oct 21. *** [6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- ? B/Snail Signal Transduction Pathway. Kim SO, Kim MR. Evid Based Complement Alternat Med. 2013;2013:761852. doi: 10.1155/2013/761852. Epub 2013 Sep 24.

Plant: Ginger (Zingiber officinale)

 

Special features of 6-gingerol:

  • Has an anticarcinogenic, anti-inflammatory and immunosuppressive effect
  • 6-Gingerol has a positive effect on asthmatic diseases
  • Could interfere with the development of tumors

6-Gingerol inhibits the expression of the cyclooxygenase-2 enzyme which is responsible for inflammation in osteoarthritis and rheumatism.

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6-Gingerol

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