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γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells. Yusof KM, Makpol S, Jamal R, Harun R, Mokhtar N, Ngah WZ. Molecules. 2015 Jun 3;20(6):10280-97. doi: 10.3390/molecules200610280. *** -gingerol dampens hepatic steatosis and inflammation in experimental nonalcoholic steatohepatitis. Tzeng TF, Liou SS, Chang CJ, Liu IM. Phytomedicine. 2015 Apr 15;22(4):452-61. doi: 10.1016/j.phymed.2015.01.015. Epub 2015 Feb 26. *** 6-Gingerol reduces Pseudomonas aeruginosa biofilm formation and virulence via quorum sensing inhibition. Kim HS, Lee SH, Byun Y, Park HD. Sci Rep. 2015 Mar 2;5:8656. doi: 10.1038/srep08656. *** 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation. Fan J, Yang X, Bi Z. Tumour Biol. 2015 Feb;36(2):1135-41. doi: 10.1007/s13277-014-2723-1. Epub 2014 Oct 21. *** -Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- ? B/Snail Signal Transduction Pathway. Kim SO, Kim MR. Evid Based Complement Alternat Med. 2013;2013:761852. doi: 10.1155/2013/761852. Epub 2013 Sep 24.
Plant: Ginger (Zingiber officinale)
- Basically like 10-Gingerol
Special features of 6-gingerol:
- Has an anticarcinogenic, anti-inflammatory and immunosuppressive effect
- 6-Gingerol has a positive effect on asthmatic diseases
- Could interfere with the development of tumors
6-Gingerol inhibits the expression of the cyclooxygenase-2 enzyme which is responsible for inflammation in osteoarthritis and rheumatism.
We open up new dimensions with phytochemicals Secondary phytochemicals are not essential for plants, but still perform important functions. These substances serve as protection against herbivores or pathogens, but also ...
Secondary Plant Ingredients
Secondary metabolites in plants are active plant ingredients, also called phytochemicals.. The demand for Phytochemicals is constantly growing not only for reference substances (for quality tests) , but for high purity ...