Article number:


CAS No.:





1,3 Dicaffeoylquinic acid; 1,5 Dicaffeylquinic acid

Molecular weight:

516,46 g/mol

Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricum L.). Topal M, Gocer H, Topal F, Kalin P, Köse LP, Gülçin I, Çakmak KC, Küçük M, Durmaz L, Gören AC, Alwasel SH. J Enzyme Inhib Med Chem. 2015 Mar 20:1-10. [Epub ahead of print] *** Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells. Xia N, Pautz A, Wollscheid U, Reifenberg G, Förstermann U, Li H. Molecules. 2014 Mar 24;19(3):3654-68. doi: 10.3390/molecules19033654. *** Inhibition of P-glycoprotein-mediated transport by S-adenosylmethionine and cynarin in multidrug-resistant human uterine sarcoma MES-SA/Dx5 cells. Angelini A, Di Pietro R, Centurione L, Castellani ML, Conti P, Porreca E, Cuccurullo F. J Biol Regul Homeost Agents. 2012 Jul-Sep;26(3):495-504. *** Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor. Dong GC, Chuang PH, Chang KC, Jan PS, Hwang PI, Wu HB, Yi M, Zhou HX, Chen HM. Pharm Res. 2009 Feb;26(2):375-81. doi: 10.1007/s11095-008-9754-5. Epub 2008 Nov 7.

Inform about


We open up new dimensions with phytochemicals Secondary phytochemicals are not essential for plants, but still perform important functions. These substances serve as protection against herbivores or pathogens, but also ...

Read more

Reference Substances

With more than 1200 substances (reference substances) Cfm Oskar Tropitzsch GmbH offers a broad range of herbal reference standards for the natural products chemistry. The portfolio consists substances from all ...

Read more