O N H N O O H O NH O O O

Duocarmycin SA

Article number:

5600181

CAS No.:

130288-24-3

Formula:

C25H23N3O7

Molecular weight:

477.47 g/mol

Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. The product demonstrates synergistic cytotoxicity against glioblastoma multiforme cells treated with proton radiation in vitro

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Duocarmycin SA

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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