O N H N O O H O NH O O O

Duocarmycin SA

Artikelnummer:

5600181

CAS Nr.:

130288-24-3

Formel:

C25H23N3O7

Molekulargewicht:

477.47 g/mol

Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. It is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. The product demonstrates synergistic cytotoxicity against glioblastoma multiforme cells treated with proton radiation in vitro. Potential mode of action/Key words: Targeting DNA, DNA alkylator, Anticancer

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Duocarmycin SA