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Satratoxin H
Article number:
5501223
CAS No.:
53126-64-0
Formula:
C29H36O9
Chemical description:
(2'S,4E,9R,10E,12Z,16R,16aS,18R,19aR,23aR,25R)-6,7,16,16a,19a,22-hexahydro-25-hydroxy-9-[(1S)-1-hydroxyethyl]-16a,21-dimethyl-spiro[5,9:16,18-dimethano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2'-oxirane]-3,14(9H)-dione
Molecular weight:
528,59 g/mol
Satratoxin H is a trichothecene mycotoxin. It has been found in Stachybotrys. Satratoxin H induces production of reactive oxygen species, increases in malondialdehyde levels and induese apoptosis in PC12 cells, when used at concentrations raning from 5 to 100 nM. Satratoxin H is cytotoxic to human umbiical veine endothelial cells as well as HepG2, A549, U937 and Jurkat cancer cells.
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