Ascochlorin

Ascochlorin is a prenylphenol natural product isolated from the Ascochyta viciae fungus that blocks the expression of matrix metalloproteinase-9 by suppressing activation of the MMP-9 gene. Ascochlorin has also been observed to bind nuclear hormone receptors, and a library of Ascochlorin derivatives showed activity as peroxisome proliferator activated receptor gamma agonists. Source Acremonium sp.