Eribulin mesylate

Artikelnummer:

5600107

CAS Nr.:

441045-17-6

Formel:

C41H63NO14S

Chemische Beschreibung:

11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-3-amino-2-hydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2R,3R,3aS, 7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-, methanesulfonate (1:1).

Synonyme:

Halaven; Eribulin mesylate; Eribulin mesilate; UNII-AV9U0660CW

Molekulargewicht:

826,00 g/mol

The research compound Eribulin mesylate is a synthetic analogue of halichondrin B, a substance derived from a marine sponge with antineoplastic activity. Eribulin inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, the induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression. Different clinical programs are currently performed.

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Eribulin mesylate

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