CAS Nr.:





[(7R,8R)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate


315,37 g/mol

Intermedine-N-oxide is a pyrrolizidine alkaloid isolated from Symphytum. Pyrrolizidine alkaloids are secondary metabolites, produced by several plant species as protection against insect herbivores. Approximately 6000 plant species worldwide may contain pyrrolizidine alkaloids. They are mainly found in the families of the Boraginaceae, Asteraceae and Fabaceae. The PA-content depends on several factors (species, plant organ, harvest, storage, extraction procedures). Contents vary from trace amounts up to 19 % based on dry weight. These alkaloids occur in two forms, as tertiary base PAs and their N-oxide (PANO). They are common food contaminants in herbs, tea, salad, leafy vegetables and honey. Feed can be contaminated so that the plant products find their way in the food chain indirectly also over meat, milk and eggs. Pyrrolizidine alkaloids have adverse health effects and were classified as genotoxic, carcinogen and hepatotoxic. [Reference: EFSA Journal 2011;9(11):2406 [134 pp.]. doi:10.2903/j.efsa. 2011.2406]

Weitere Produkte

Artikelnummer: 7501610
CAS Nr.: 10285-06-0
Formel: C15H25NO5
Molekulargewicht: 299,36 g/mol

Artikelnummer: 7500660
CAS Nr.: 480-81-9
Formel: C18H23NO5
Molekulargewicht: 333,38 g/mol

Artikelnummer: 7500573
CAS Nr.: 38710-26-8
Formel: C18H23NO6
Molekulargewicht: 349,38 g/mol

Artikelnummer: 8000736

Informieren Sie sich über


Mit mehr als 1200 pflanzlichen Referenzsubstanzen (Phyto Referenzsubstanzen) bietet die Cfm Oskar Tropitzsch GmbH ein breites Produktspektrum für die Naturstoffchemie an. Das umfangreiche Sortiment beinhaltet Substanzen aller Naturstoffklassen, als auch ...

Mehr erfahren