Active ingredient of the month August: Everolimus
Our versatile active ingredient of the month for August, everolimus, is used in various medical fields. Originally developed as an immunosuppressant, everolimus has become increasingly important in oncology. Mode of action: suppresses cell proliferation and immune response of the body Everolimus belongs to the class of mTOR inhibitors (mammalian target of rapamycin). It binds to […]
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Active ingredient of the month for July: paclitaxel
Our active ingredient of the month, paclitaxel, is used to treat various types of cancer. Paclitaxel is able to inhibit the division and proliferation of cancer cells. Cytostatic agent from the Pacific oak Paclitaxel is a cytostatic agent and belongs to the group of taxanes. It is extracted from the bark of the Pacific yew […]
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Resiniferatoxin – the world’s hottest chemical in painkiller research
Resiniferatoxin is a natural substance found in Euphorbia resinifera. This plant grows in Morocco on the slopes of the Atlas Mountains. The milky sap of this plant contains a high concentration of resiniferatoxin.Resiniferatoxin has a taste that is 500 to 1000 times hotter than capsaicin, which is found in peppers or chili.On the Scoville scale, […]
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Active ingredient of the month for June: Yohimbine – natural sexual enhancer from West Africa
Even before the invention of the potency pill, men relied on natural aids, such as yohimbine. This active ingredient is extracted from the leaves and bark of the yohime tree in Africa. Natural alternative to PDE-5 inhibitors In times of Viagra & Co., yohimbine has moved somewhat into the background. But in today’s world, conscious […]
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Purpurin 18: A natural anthraquinone with special pharmacological activities
Purpurin 18 is a derivative of chlorophyll, a natural pigment found in green plants and algae.It can be easily isolated from all kinds of green plants and, thus, it presents an economically feasible source. Selective destruction of cancer cells possible Purpurin 18 has been studied as a potential photosensitizer for photodynamic therapy (PDT),This therapy uses […]
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Active ingredient of the month May: Etofenamate
The non-steroidal anti-inflammatory etofenamate belongs to the group of anthranilic acid derivatives with analgesic properties. Etofenamate has a fast effect because it is well absorbed through the skin. Because it is applied locally, systemic side effects are less common compared to orally administered NSAIDs. Etofenamate is a yellowish, viscous liquid that is virtually insoluble in […]
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Active ingredient of the month April: Bisacodyl
Our active ingredient of the month, Bisacodyl, belongs to the group of laxatives. In the form of enteric-coated tablets or suppositories, it is usually used for a short time for constipation – since the 1950s. Special feature: dual mechanism of action Bisacodyl offers a dual mechanism of action: on the one hand, it stimulates the […]
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From scouting to project management: We support your innovation process
Scarcity of raw materials, legal requirements, patent expirations, increasing competition, global pressure. These are challenges that almost every industry faces. In particular, the pharmaceutical and chemical industries. This is aggravated by pronounced regulatory requirements. Pharmaceutical industry: Expenditure on research and development particularly high Regulations and safety standards are constantly changing. Pharmaceutical and chemical companies must […]
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Active ingredient of the month March: Sodium hyaluronate
Sodium hyaluronate or hyaluronic acid is an endogenous substance that is mainly found in joints and connective tissue. Together with water, hyaluronic acid forms a viscous gel, making it the ideal lubricant in the body. Astonishingly, one gram of hyaluronic acid is able to bind up to six liters of water. This extraordinary storage capacity […]
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Active ingredient of the month February: Bee venom
For centuries, traditional medicine has used honeybee venom for its anti-inflammatory effects. Of central importance is the main ingredient melittin. Melittin: A hundred times stronger than cortisone The melittin from the venom of the honey bee has long been known for its strong effect in laboratory experiments. In case of inflammation, it has a hundred […]
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Glycoalkaloids: Potatoes and tomatoes as potential drug suppliers against cancer
The solanine contained in potatoes is one of the glycoalkaloids (naturally occurring phytochemicals). Nightshade plants produce these substances to ward off pests and pathogens. The bioactive compounds can also be toxic to humans. However, researchers have now found that in therapeutic doses, they cause cancer cells to die and suppress the formation of metastases. According […]
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Active ingredient of the month January: Sirolimus
Sirolimus, also known as rapamycin, is an immunosuppressant and mTOR inhibitor with a macrolide structure. It is a product of the streptomycete Streptomyces hygroscopicus. This species of bacteria was first isolated from the soil of the island of Rapa Nui. Active ingredient from Easter Island avoids restenosis in stents Sirolimus is indicated for: Prophylaxis of […]
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