Avarol from sea sponges
Did you know that sea sponges produce drugs? Every day they protect themselves against their natural enemies with a multitude of active ingredients. Some of these substances, like Avarol, are already used successfully against viral diseases or cancer. Researchers are now trying to breed the sea sponges in order to obtain larger quantities of the […]
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IPTG (Isopropyl-β-d-thiogalactopyranosid) – Use in Molecular Biology
The synthetic carbohydrate isopropyl-β-D-thiogalactopyranoside (IPTG) is the isopropylthioglycoside of D-galactose. This reagent is particularly widespread in recombinant protein expression. This substance is often used in molecular biology. IPTG – important for the lactose metabolism of Escherichia coli This lac operon plays an important role in the lactose metabolism of various enteric bacteria, such as Escherichia […]
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Verrucarin A in cancer therapy
Pancreatic cancer (ductal pancreatic adenocarcinoma / PDA) is one of the most difficult cancers to treat. Common chemotherapeutic agents often only bring about a short-term improvement in symptoms and, unfortunately, experience has shown that they have little effect on the patient’s recovery. New types of therapy are urgently needed here. This is where Verrucarin A […]
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DL-Dithiothreitol – DTT as key element in diagnostics
In today’s time when there is still no vaccine or medication against the corona virus, COVID 19 tests or antibody tests are particularly important in order to uncover and thus interrupt the chain of infection. One product is of particular importance in these test kits: DL-Dithiothreitol, in short: DTT Long-term partnership Cfm Oskar Tropitzsch GmbH […]
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Sirolimus – An accompanying treatment for COVID-19 in elderly persons?!
Researchers globally combat the COVID-19 pandemia. Data generated suggest that COVID-19 is a major threat for elderly in regards to being more dangerous and more severe. Even when a successful vaccine for SARS-CoV-2 becomes available, an additional drug might be necessary in order to boost the immune response in vaccinated but weakened persons. Rapamycin/Sirolimus is […]
Read moreRapamycin – Eine Zusatztherapie bei der COVID-19 Behandlung von Senioren?!
Forscher weltweit bekämpfen die COVID-19-Pandämie. Die generierten Daten legen nahe, dass COVID-19 eine große Bedrohung gerade für ältere Menschen darstellt, da die Krankheitsverläufe gefährlicher und schwerer sind. Selbst wenn ein erfolgreicher Impfstoff gegen SARS-CoV-2 verfügbar wird, kann ein zusätzliches Medikament erforderlich sein, um die Immunantwort bei geimpften, aber geschwächten Personen zu stärken. Rapamycin / Sirolimus […]
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Sirolimus API
Sirolimus / Rapamycin for facial angiofibromas A Sirolimus vaseline® 0.1% jelly produced by pharmacies according to an prescription shows success in the treatment of facial angiofibromas. Facial angiofirbomas are a symptom of tuberous sclerosis (TSC also Pringle-Bourneville disease). Tuberous sclerosis is a multi-system disease. At least for the treatment of facial angiofibromas, a rapamycin vaseline® […]
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Combat COVID-19 with the natural compound OSW-1!?
Oxysterol-binding Protein (OSBP), required for the cellular replication of many types of viruses can be inhibited by the natrual compound (OSW-1). The OSW-1 induced reduction of OSBP inhibit Enterovirus replication prophylactically in cells. These are the findings published in Antiviral Research 117 (2015) 110-114 and Antiviral Research 170 (2019) 104548. We assume, that COVID-19 (CORONAVIRUS) […]
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Alpine Winter Conference
Visit us at the 2nd Alpine Winter Conference in St. Anton, taking place Jan. 19.- Jan 23, 2020 The Conference topics will include: Accelerating Drug Discovery by Intelligence Augmentation Drug Discovery Tales Frontiers of Synthetic Chemistry Innovation and Inspiration from Natural Products Predictive ADME Sciences: Striking a Balance Between in Silico and Experimental Work? Protein […]
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Excipients – An utmost important substance class
High quality supply of Excipients with (no) or less variations – this is what Cfm Oskar Tropitzsch GmbH offers to its clients. Excipients are utmost substantial ingredients in drug products. The Excipients can be sometimes determinant for the activity of the final drug product. Even if this substance class is sometimes only seen as a […]
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Rapamycin – Active Pharmaceutical Ingredient
We are pleased to offer Rapamycin as GMP/API grade (active pharmaceutical ingredient) in small quantities (5 g / 25 g). Especially pharmacies working in the field of Tuberous Sclerosis treatment (TSC, Tuberous Sclerosis Complex, Pringle-Bournveville’s disease), we would like to offer the best EU pharmaceutical quality in acceptable quantities. For drug-eluting stents (DES) coating companies, […]
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14th Annual Drug Discovery Chemistry
Visit Cfm Oskar Tropitzsch GmbH at Booth #: 318 14th Annual Drug Discovery Chemistry is a dynamic conference for medical chemists working in pharma and biotech. Focused on discovery and opimization challenges of small molecule drug candidates, this event provides many exciting opportunities for scientists to create a unique program to hear presenations most suited […]
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