Hesperetin

The pleiotropic effects of fisetin and hesperetin on human acute promyelocytic leukemia cells are mediated through apoptosis, cell cycle arrest, and alterations in signaling networks.Adan A, Baran Y. Tumour Biol. 2015 Jun 17. [Epub ahead of print]***Hesperetin Induces the Apoptosis of Gastric Cancer Cells via Activating Mitochondrial Pathway by Increasing Reactive Oxygen Species.Zhang J, Wu D, Vikash, Song J, Wang J, Yi J, Dong W. Dig Dis Sci. 2015 May 14. [Epub ahead of print]***Hesperetin induces melanin production in adult human epidermal melanocytes.Usach I, Taléns-Visconti R, Magra ner-Pardo L, Peris JE. Food Chem Toxicol. 2015 Jun;80:80-4. doi: 10.1016/j.fct.2015.02.017. Epub 2015 Mar 9.***Hesperetin induces the apoptosis of hepatocellular carcinoma cells via mitochondrial pa thway mediated by the increased intracellular reactive oxygen species, ATP and calcium.Zhang J, Song J, Wu D, Wang J, Dong W. Med Oncol. 2015 Apr;32(4):101. doi: 10.1007/s12032-015-0516-z. Epub 2015 Mar 4.***Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.Roohbakhsh A, Parhiz H, Soltani F, Rezaee R, Iransh ahi M. Life Sci. 2015 Mar 1;124:64-74. doi: 10.1016/j.lfs.2014.12.030. Epub 2015 Jan 24. Review.***Hesperetin Induces Apoptosis in Breast Carcinoma by Triggering Accumulation of ROS and Activation o f ASK1/JNK Pathway.Palit S, Kar S, Sharma G, Das PK. J Cell Physiol. 2015 Aug;230(8):1729-39. doi: 1