36_mycotoxin

Mykotoxine

Besuchen Sie uns beim 38. Mycotoxin Workshop in Berlin. Einige Themen dieser Veranstaltung: -Identification of Stachybotrys spp. -Occuring of mycotoxins (DON, ZEA) in feeding stuff from farms in the German state of Brandenburg -Mycotoxin production of moulds on bread and cheese under household conditions -How toxic is the air? – Methods for sampling and detection of mycotoxins […]

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Magnesium Oxide

Most of the Metal Compounds are commodities and are easy to source. Magnesium Oxide is one of these products. Magnesium Oxide, CAS: 1309-48-4 Chemical Formula: MgO Molecular weight: 40,30 g/mol The problem of those common products is not to find a source, but often it’s hard to find material which is suitable for none common […]

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Bulk quantities: Monomethyl auristatin E (MMAE)

Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. The family of auristatins are synthetic analogues of the antineoplastic natural product Dolastatin 10. MMAE is 100-1000 times more potent than Doxorubicin. Now available: Together with our European partner we realized a bulk production for MMAE, MMAF (Monomethyl […]

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Asiaticoside – appealing for cosmetic and pharma

Research is focusing on its pharmacological properties: anti-depression, anti-inflammatory and anti-tumor. Recently revealed activities are the protection of nerve cells, inhibition of apoptosis of neural cells and improvement of memory. Sun et al showed the nerve protective effect of Asiaticoside in an ischemia-hypoxia cell model in vitro. Asiaticoside reduced the lactate dehydrogenase level and also […]

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Antibody Drug Conjugates (ADCs) – Cytotoxins

PhenoFrag – ADC-latest news

To analyze all these effects and interactions is impossible without a valid, fast and reliable system. If you have new ideas for Payloads, APIs, try our PhenoFrag to generate the data which provides you with the answers you need to speed up your drug development. Interested? Please just get in touch with us. PhenoFrag:  Develops […]

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Astragalus membranaceus and its Astragalosides

Of two recently published studies, one is focusing on the effect of Astragalus membranaceus on colorectal cancer. The antitumor effect was assessed on subcutaneous tumors of human colorectal cancer cell line grafted into nude mice. The profiling of the microarray expression of the tumors showed its potential as a therapeutic drug. Another publication discusses the […]

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Finding the best solution for you! …but what’s behind this phrase?

First of all you define the specifications and quality requirements which you need – not what might be available. The customer – so just you – defines the quantity: from lab scale to commercial scale. Securing supply: projects start always with small quantity requirements and increasing demand for material and documentation throughout the lifecycle of […]

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28. Irseer Naturstofftage

24. – 26. Februar 2016 Kloster Irsee, Deutschland Cfm Oskar Tropitzsch GmbH nimmt an den diesjährigen 28. Naturstofftagen im Kloster Irsee teil. Wir freuen uns auf interessante Gespräche und einen angenehmen Gedankenaustausch. Biologisch aktive Naturstoffe sind sowohl in der Grundlagenforschung als auch in der Forschung und Entwicklung der Pharma- und Agroindustrie von großer Bedeutung. Als […]

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adcberlin

world adc berlin 2016

8.- 10. Februar 2016 Berlin, Deutschland Besuchen Sie uns im Maritim proArte Hotel. Themen des Events sind u.a.: – Discover ADC Payloads with Differentiated Mechanisms of Action‘ – Advance Clinical Scale Manufacturing – Effectively Translate into the Clinic Finden Sie neue Moleküle für Payloads. Wir freuen uns auf Ihren Besuch!

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Weihnachtsgrüße aus Marktredwitz

Weichnachtsgrüße von Cfm Oskar Tropitzsch GmbH Das Team der Cfm Oskar Tropitzsch bedankt sich für die gute und freundschaftliche Zusammenarbeit im zu Ende gehenden Jahr 2015. Auf dem Bild sehen Sie die „gute Stube“ von Marktredwitz, den Markt. Im Jahr 2016 feiert Marktredwitz „200 Jahre in Bayern“ – ein weiterer Grund für einen Besuch bei […]

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Drug Development – 7. Kooperationsforum

The forum offers people from industry and science to get in contact and access to topic information regarding the following key aspects: Antibiotic therapy and resistance Development of new antiinfektiva Libraries of active ingredients Nucleotide-based therapeutic and vaccination  Sepsis diagnosis Mobile lab to fight against Ebola

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Paeonol – an actor against cancer related inflammation (CRI)

In mouse melanoma cells paeonol had an effect on cell proliferation, apoptosis and the secretion of proinflammatory cytokines, like TNF-α, IL-1β, IL-6 and TGF-β. In vivo the results showed an attenuation of lung metastases accompanied by a downregulation of proinflammatory cytokines in the serum. The authors indicate that the anti-tumor activity of this compound is […]

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