Beta-Amanitin – a potential payload for antibody drug conjugates (ADCs)
beta-Amanitin is an inhibitor of eukaryotic RNA polymerase II and RNA polymerase III, but not RNA polymerase I or bacterial RNA polymerase. It inhibits mammalian protein synthesis. These properties make it interesting as a new potential drug for ADC research. α-Amanitin is already known as effective payload for ADCs. beta-Amanitin has a comparable biological activity […]
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Funktionelle Inhaltsstoffe
Das Forum bietet Kontakt zu Partnern aus Industrie und greift folgende Themenschwerpunkte auf: Entwicklung pflanzlicher Wirkstoffe auf Basis traditioneller Heilpflanzen Data Mining zur Identifizierung bioaktiver Naturstoffe Nachweis der Bioaktivität für gesunde Ernährungskonzepte Nanomaterialien im Lebensmittelsektor Nicht-invasive Lebensmittelanalytik mittels Raman-Spektroskopie Textile Freisetzungssysteme Funktionalisierung von Lebensmittelverpackungen und verbesserte Barriereeigenschaften 3D-Food Printing und Industrie 4.0 Konzepte im Lebensmittelsektor Ziel des Forums Ziel ist […]
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Zinc oxide
Hatamie A et al. showed that a ZnO-based textile has photocatalytic and antibacterial activities. In addition the textile exhibited a promising sensing response. The modified textile was created by direct in situ growth of vertically aligned one-dimensional ZnO NRs onto textile surfaces. The effects provided by ZnO are a new approach to create smart textiles: […]
Mehr erfahrenFish oil
Fish oil is a source of anti-inflammatory effects, mediated by n-3 PUFA (polyunsaturated fatty acids). The authors showed that dietary fish oil is able to attenuate hepatic inflammation and ER stress-induced UPR (unfolded protein response) in the liver of lactating sows. In the fish oil group mRNA levels of a number of UPR-regulated genes were […]
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World adc San Diego 2015
20. – 21. Oktober 2015 San Diego, CA, USA Besuchen Sie uns im San Diego Marriott Marquis & Marina. Themen des Events sind u.a.: – Optimize linker payload compatibility – Improve preclinical predictability – Maximize clinical efficacy Finden Sie neue Moleküle für Payloads. Wir freuen uns auf Ihren Besuch! About WORLD adc: World ADC San Diego has been […]
Mehr erfahrenGinseng and its ginsenosides
Stroke, Alzheimer´s disease, Parkinson disease, major depression and multiple sclerosis. Diseases where science is still investigating treatment possibilities – Ginseng could be a solution. It belongs to one of the oldest traditional herbal medicines, known for over 2000 years as anti-anxiety, antidepressant and cognition enhancing. The ginseng root includes more than 60 ginsenosides, e.g. Rb1, […]
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CPhI Madrid 2015
13. – 15. Oktober 2015 Madrid, Spanien Treten Sie mit uns in Kontakt und vereinbaren Sie ein Treffen mit uns auf der CPhI worldwide vom 13. – 15. Oktober 2015 in Madrid. Falls Sie schon im voraus einen Termin vereinbaren möchten, setzen Sie sich bitte via email: info@cfmot.de oder per Tel. 09231/9619-0 in Verbindung. Wir […]
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Drug Conjugates for Directed Therapy – Bielefeld
20. – 23. September 2015 Center for Interdisciplinary Research (ZiF), Uni Bielefeld Themen dieser Veranstaltung sind u. a.: *Antibody-Drug Conjugates *Peptide-Drug Conjugates *Targets and Specificity *New Drugs *Linker Technologies *Applications *Process Development Wir freuen uns auf interessante Gespräche.
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XIXth International Congress „Phytopharm 2015“
New Phytotherapeutics – Developments, Requirements and Success for Patients with Rational Phytotherapy and courses „GxP in biomedical research“ July 21-24, 2015 in Bonn, Germany Cfm Oskar Tropitzsch GmbH will participate at the international congress “Phytopharm 2015”, July 22-24 2015 in Bonn, Germany. We would be glad to meet you.
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Novel application for Rapamycin / Siroliums
Rapamycin is used since many years in different pharmaceutical applications. Some examples are the prevention of transplant rejection as well as the coating of coronary stents. Now Sirolimus also shows promise in treating tuberous sclerosis complex, in special facial angiofibromas. An easy to compound and to apply rapamycin cream shows dramatic improvement of this tuberous […]
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Fisetin and Hesperetin
The flavonoids fisetin and hesperetin have several pharmaceutical effects, like antioxidative and anti-inflammatory. Fisetin is also known for being neuroprotective and a promising agent for Alzheimer-treatment. A recent publication is concentrating on the anti-leukemia property of these two phytochemicals. Adan A. et al. have investigated the antiproliferative and apoptotic actions on human HL60 acute promyelocytic […]
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RICT 2015 – Avignon
1. – 3. Juli 2015 Avignon, Frankreich Université d`Avignon et des Payes de Vaucluse Cfm Oskar Tropitzsch nimmt an der diesjährigen International Conference on Medicinal Chemistry teil. Besuchen Sie uns an unserem Stand #31 —- The French Medicinal Chemistry Society (Société de Chimie Thérapeutique – SCT) is pleased to invite you to Avignon, for the […]
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